Abstract
Highly specific and sensitive fluorescence detection of hypochlorite in nonbiotic pure water (rapid "turn-on", ~400 fold, λ(em) ~ 560 nm) as well as in living neuronal cell cultures (neutral pH) involves oxidation of a 2-sulfide-2-benzoic acid pendent group in a new meso-thienyl-BODIPY donor-acceptor probe.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Benzenesulfonates / chemistry
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Benzoates / chemistry
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Boron Compounds / chemistry*
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Cell Survival
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Esterases / metabolism*
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Fluorescence*
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Fluorescent Dyes / chemistry*
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Humans
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Hypochlorous Acid / analysis*
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Microscopy, Fluorescence
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Molecular Structure
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Neuroblastoma / enzymology*
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Neuroblastoma / metabolism
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Neuroblastoma / pathology
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Oxidation-Reduction
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Reactive Oxygen Species / metabolism
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Tumor Cells, Cultured
Substances
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4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
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Benzenesulfonates
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Benzoates
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Boron Compounds
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Fluorescent Dyes
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Reactive Oxygen Species
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Hypochlorous Acid
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Esterases
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2-sulfobenzoic acid