Metabolic hypertension: concept and practice

Front Med. 2013 Jun;7(2):201-6. doi: 10.1007/s11684-013-0264-4. Epub 2013 Apr 5.

Abstract

Hypertension is a serious public health problem worldwide. More than 60% of the risk factors for hypertension are associated with metabolic disturbances. Metabolic abnormalities increase the risk for hypertension and cause high blood pressure. Improving metabolic disturbances is beneficial for hypertension treatment. Due to the importance of metabolic abnormalities in the pathogenesis of hypertension, we propose a concept of metabolic hypertension. In this review, we discuss and review the clinical types, pathogenesis, risk evaluation and management of metabolic hypertension. Elucidation of the mechanism of metabolic hypertension should facilitate the design of novel pharmacotherapeutics and dedicated antihypertensive manipulations.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Humans
  • Hypertension / drug therapy
  • Hypertension / etiology*
  • Hypertension / metabolism*
  • Metabolic Diseases / complications*
  • Metabolic Diseases / drug therapy
  • Metabolic Diseases / metabolism*
  • Risk Factors

Substances

  • Antihypertensive Agents