Insulin and ventral tegmental dopamine: what's impaired and what's intact?

John D Salamone; Mercè Correa

doi:10.1016/j.cmet.2013.03.011

Insulin and ventral tegmental dopamine: what's impaired and what's intact?

Cell Metab. 2013 Apr 2;17(4):469-70. doi: 10.1016/j.cmet.2013.03.011.

Authors

John D Salamone¹, Mercè Correa

Affiliation

¹ Department of Psychology, University of Connecticut, Storrs, CT 06269-1020, USA. john.salamone@uconn.edu

PMID: 23562071
DOI: 10.1016/j.cmet.2013.03.011

Abstract

Manipulations affecting mesolimbic dopamine transmission exert specific effects on normal and pathological aspects of motivation, altering some functions while sparing others. Labouèbe et al. (2013) show that insulin induced long-term depression in ventral tegmental neurons, which was associated with reduced responsiveness to food-related stimuli but spared aspects of food-seeking behavior.

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