Single-molecule detection of 5-hydroxymethylcytosine in DNA through chemical modification and nanopore analysis

Angew Chem Int Ed Engl. 2013 Apr 15;52(16):4350-5. doi: 10.1002/anie.201300413. Epub 2013 Apr 4.

Authors

Wen-Wu Li¹, Lingzhi Gong, Hagan Bayley

Affiliation

¹ Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK.

PMID: 23559386
DOI: 10.1002/anie.201300413

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

5-Methylcytosine / analogs & derivatives
Cytosine / analogs & derivatives*
Cytosine / analysis
Cytosine / chemistry
DNA / chemistry*
Molecular Structure
Nanopores*

Substances

5-hydroxymethylcytosine
5-Methylcytosine
Cytosine
DNA