Palladium-catalyzed desulfitative cross-coupling reaction of sodium sulfinates with benzyl chlorides

Feng Zhao; Qi Tan; Fuhong Xiao; Shufeng Zhang; Guo-Jun Deng

doi:10.1021/ol400295z

Palladium-catalyzed desulfitative cross-coupling reaction of sodium sulfinates with benzyl chlorides

Org Lett. 2013 Apr 5;15(7):1520-3. doi: 10.1021/ol400295z. Epub 2013 Mar 13.

Authors

Feng Zhao¹, Qi Tan, Fuhong Xiao, Shufeng Zhang, Guo-Jun Deng

Affiliation

¹ Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China.

PMID: 23556515
DOI: 10.1021/ol400295z

Abstract

A palladium-catalyzed approach for the synthesis of diarylmethanes from sodium sulfinates and benzyl chlorides is described. Various aromatic sodium sulfinates were used as aryl sources via extrusion of SO2 and gave the diarylmethanes in moderate to good yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzyl Compounds / chemistry*
Catalysis
Combinatorial Chemistry Techniques
Magnetic Resonance Spectroscopy
Molecular Structure
Palladium / chemistry*
Sodium / chemistry*
Sulfinic Acids / chemistry*
Sulfur Dioxide / chemistry

Substances

Benzyl Compounds
Sulfinic Acids
Sulfur Dioxide
Palladium
benzyl chloride
Sodium