Abstract
Writer's blocks: The first synthesis of RNA purine building blocks, 4'-selenoadenosine and 4'-selenoguanosine was achieved from D-ribose by regioisomeric rearrangement, which was confirmed by X-ray crystallography. 4'-Selenoadenosine exists in an unusual mixture of north and south conformers in the solid state.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenosine / analogs & derivatives*
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Adenosine / chemical synthesis
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Adenosine / chemistry
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Crystallography, X-Ray
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Guanosine / analogs & derivatives*
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Guanosine / chemical synthesis
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Guanosine / chemistry
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Molecular Conformation
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Molecular Structure
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Nucleosides / chemical synthesis*
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Nucleosides / chemistry
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Organoselenium Compounds / chemical synthesis*
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Organoselenium Compounds / chemistry
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Purines / chemical synthesis*
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Purines / chemistry
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RNA / chemistry*
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Ribose / chemistry*
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Stereoisomerism
Substances
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4'-selenoadenosine
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4'-selenoguanosine
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Nucleosides
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Organoselenium Compounds
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Purines
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Guanosine
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RNA
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Ribose
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Adenosine