Segmental cherry angiomas associated with extragenital lichen sclerosus: a report of two cases

Clin Exp Dermatol. 2013 Jun;38(4):386-9. doi: 10.1111/j.1365-2230.2012.04479.x. Epub 2013 Apr 3.

Abstract

Cherry angiomas (Campbell de Morgan spots) are common acquired red skin papules composed of dilated capillary loops, usually of unknown aetiology. Extragenital lichen sclerosus (LS) presents as porcelain-white scaly atrophic lesions with or without genital involvement. We report two cases of segmental multiple cherry angiomas in association with extragenital LS. Two unrelated women, aged 46 and 66 years, presented with extragenital LS affecting their axillae and lower abdomen. During the examination, both patients were noted to have several hundred red skin papules in a segmental distribution, affecting the left thigh and flank of one woman, and the right abdomen and back of the other. Clinically and histologically, the papules were consistent with cherry angiomas. The striking segmental distribution of multiple cherry angiomas may be due to genetic mosaicism; however, segmental Fabry disease was excluded by sequence analysis of the α-galactosidase A gene. Any causal link between cherry angiomas and LS remains uncertain.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Hemangioma / complications*
  • Hemangioma / pathology
  • Humans
  • Lichen Sclerosus et Atrophicus / complications*
  • Lichen Sclerosus et Atrophicus / pathology
  • Middle Aged
  • Skin Neoplasms / complications*
  • Skin Neoplasms / pathology