Abstract
The rapid response of integrin β1 molecules to an RGD peptide on a dynamic polyrotaxane surface was successfully induced. As a result, RGD peptides introduced on a highly dynamic cyclodextrin molecule enhanced the frequency of contact with specific integrin molecules on the cell membrane at the early stage of material-cell interactions.
MeSH terms
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Cell Adhesion
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Human Umbilical Vein Endothelial Cells / cytology
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Human Umbilical Vein Endothelial Cells / metabolism
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Humans
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Integrins / metabolism
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Oligopeptides / metabolism*
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Surface Properties
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Time Factors
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alpha-Cyclodextrins / metabolism
Substances
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Integrins
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Oligopeptides
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alpha-Cyclodextrins
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arginyl-glycyl-aspartic acid