A case of CMV endotheliitis treated with intravitreal ganciclovir injection

Korean J Ophthalmol. 2013 Apr;27(2):130-2. doi: 10.3341/kjo.2013.27.2.130. Epub 2013 Feb 27.

Abstract

We report a case of CMV corneal endotheliitis that was treated with intravitreal ganciclovir injection. A 56-year-old man who has suffered from uveitis was referred to our clinic due to corneal endothelial abnormality. Slit lamp examination showed a localized sectoral corneal edema and linear keratic precipitates along the boundary of edema. In spite of treatment with oral steroid and acyclovir, the disease progressed and two new coin-like lesions were developed. After topical ganciclovir and intavitreal injection of ganciclovir, the corneal lesions disappeared.

Keywords: CMV endotheliitis; Intravitreal ganciclovir injection.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / administration & dosage
  • Cytomegalovirus Infections / complications*
  • Cytomegalovirus Infections / drug therapy*
  • Endothelium, Corneal / virology*
  • Ganciclovir / administration & dosage*
  • Humans
  • Intravitreal Injections
  • Keratitis / drug therapy*
  • Keratitis / virology*
  • Male
  • Middle Aged

Substances

  • Antiviral Agents
  • Ganciclovir