Genomic sequence analysis of a new reassortant infectious bursal disease virus from commercial broiler flocks in Central China

Arch Virol. 2013 Sep;158(9):1973-8. doi: 10.1007/s00705-013-1682-y. Epub 2013 Mar 31.

Abstract

We report the complete nucleotide sequence of a reassortant infectious bursal disease (IBD) virus (IBDV) HN isolate from commercial broiler flocks in central China. The genome consisted of 3,232 and 2,652 nucleotides in the coding regions of segments A and B, respectively. Alignment of both nucleotide and deduced amino acid sequences and phylogenetic analysis revealed that the genome segments A and B of HN were derived from the attenuated strain B87 and the VV strain OKYM. This is a new reassortant IBDV strain that has emerged in nature, involving segment A of a cell-culture-adapted attenuated vaccine strain B87.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Birnaviridae Infections / veterinary*
  • Birnaviridae Infections / virology
  • Chickens / virology*
  • China
  • Genome, Viral / genetics*
  • Infectious bursal disease virus / classification
  • Infectious bursal disease virus / genetics*
  • Infectious bursal disease virus / immunology
  • Infectious bursal disease virus / isolation & purification
  • Infectious bursal disease virus / pathogenicity
  • Open Reading Frames
  • Phylogeny
  • Poultry Diseases / virology*
  • RNA, Viral / genetics
  • Reassortant Viruses / genetics*
  • Sequence Analysis, DNA*
  • Vaccines, Attenuated / genetics*
  • Vaccines, Attenuated / immunology

Substances

  • RNA, Viral
  • Vaccines, Attenuated