Enterotoxigenic Bacteroides fragilis causes lethal colitis in Mongolian gerbils

Sejin Yim; Sun-Yeong Gwon; Soonjae Hwang; Nae Hyeon Kim; Bae Dong Jung; Ki-Jong Rhee

doi:10.1016/j.anaerobe.2013.03.008

Enterotoxigenic Bacteroides fragilis causes lethal colitis in Mongolian gerbils

Anaerobe. 2013 Jun:21:64-6. doi: 10.1016/j.anaerobe.2013.03.008. Epub 2013 Mar 26.

Authors

Sejin Yim¹, Sun-Yeong Gwon, Soonjae Hwang, Nae Hyeon Kim, Bae Dong Jung, Ki-Jong Rhee

Affiliation

¹ Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University at Wonju, Wonju, Gangwon-do 220-710, Republic of Korea.

PMID: 23538057
DOI: 10.1016/j.anaerobe.2013.03.008

Abstract

Enterotoxigenic Bacteroides fragilis (ETBF) causes inflammatory diarrhea in humans and livestock and is implicated in colorectal cancer. In this report, we show for the first time that ETBF can induce profuse diarrhea and an acute, lethal colitis in Mongolian gerbils.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bacteroides Infections / microbiology*
Bacteroides fragilis / isolation & purification*
Bacteroides fragilis / pathogenicity
Cecum / microbiology
Cecum / pathology
Colitis / microbiology
Colitis / mortality
Colitis / veterinary*
Colon / microbiology
Colon / pathology
Diarrhea
Enterotoxins
Feces / microbiology
Female
Gerbillinae*
Humans
Intestine, Small / microbiology
Intestine, Small / pathology
Rodent Diseases / microbiology*

Substances

Enterotoxins