Fabrication of hand-in-hand nanostructure for one-step protein detection

Chem Commun (Camb). 2013 May 8;49(36):3760-2. doi: 10.1039/c3cc40543e. Epub 2013 Mar 27.

Abstract

A new strategy to fabricate an aptamer-protein nanowire at an electrode surface is reported in this paper, and a simple electrochemical method to determine the concentration of a protein is proposed with high sensitivity and selectivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide / chemistry
  • Coordination Complexes / chemistry
  • DNA Probes / chemistry
  • DNA Probes / metabolism
  • Electrochemical Techniques*
  • Electrodes
  • Gold / chemistry
  • Nanostructures / chemistry*
  • Nanowires / chemistry
  • Oxidation-Reduction
  • Proteins / analysis*
  • Proteins / chemistry
  • Ruthenium / chemistry
  • Sulfhydryl Compounds / chemistry

Substances

  • Aptamers, Nucleotide
  • Coordination Complexes
  • DNA Probes
  • Proteins
  • Sulfhydryl Compounds
  • Gold
  • Ruthenium