Spontaneous high-grade glial intramedullary tumor of the spine in a rhesus macaque (Macaca mulatta)

J Med Primatol. 2013 Jun;42(3):158-60. doi: 10.1111/jmp.12045. Epub 2013 Mar 28.

Abstract

Background: A 4-year-old rhesus macaque presented with acute, progressive paresis of the extremities.

Methods: A complete blood count, serum biochemical analysis, neurologic exam and necropsy were performed.

Results: The clinical, histopathological, and immunohistochemical findings confirmed a high-grade intramedullary glial tumor of the spinal cord that was most consistent with an ependymoma.

Conclusions: We describe a case of a naturally occurring spontaneous spinal cord neoplasia in a non-human primate.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Ependymoma / complications
  • Ependymoma / diagnosis
  • Ependymoma / veterinary*
  • Fatal Outcome
  • Female
  • Macaca mulatta*
  • Monkey Diseases / diagnosis*
  • Monkey Diseases / etiology
  • Paresis / diagnosis
  • Paresis / etiology
  • Paresis / veterinary*
  • Spinal Cord / pathology
  • Spinal Cord Neoplasms / complications
  • Spinal Cord Neoplasms / diagnosis
  • Spinal Cord Neoplasms / veterinary*