Reversible hypothalamic dysfunction in optic nerve germinoma

J Craniofac Surg. 2013 Mar;24(2):468-9. doi: 10.1097/SCS.0b013e318275eb2b.

Abstract

Primary optic apparatus germ cell tumors are rare. There have been only 6 cases reported in the literature. Although they often disturb the hypothalamus-pituitary-adrenal axis and cause progressive visual loss, the influence of treatment outcomes on hypothalamic autoregulation has never been mentioned. Here, we report a patient with an optic nerve germinoma who presented with reversible visual and hypothalamic dysfunction, and we discuss the possible mechanisms and pathogenesis.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Female
  • Germinoma / complications
  • Germinoma / diagnosis
  • Germinoma / radiotherapy*
  • Humans
  • Hypothalamus / physiopathology*
  • Optic Nerve Neoplasms / complications
  • Optic Nerve Neoplasms / diagnosis
  • Optic Nerve Neoplasms / radiotherapy*
  • Vision Disorders / etiology
  • Young Adult