Cross-recognition of aspergillus galactomannan caused by Listeria monocytogenes infection

Diagn Microbiol Infect Dis. 2013 Jun;76(2):250-1. doi: 10.1016/j.diagmicrobio.2013.02.005. Epub 2013 Mar 19.

Abstract

We report a case of Listeria monocytogenes bacteremia in a leukemic patient having a positive assay for aspergillus galactomannan (GM), although no evidence of aspergillosis was found. Supernatant obtained from L. monocytogenes strain suspension was reactive with GM-assay. L. monocytogenes produces a soluble antigen that is cross-reactive with Aspergillus GM.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Antigens, Fungal / blood*
  • Antineoplastic Agents / therapeutic use
  • Aspergillosis / diagnosis
  • Aspergillus / chemistry*
  • Bacteremia / drug therapy
  • Bacteremia / microbiology*
  • Cross Reactions
  • Galactose / analogs & derivatives
  • Humans
  • Leukemia / drug therapy
  • Leukemia / immunology
  • Leukemia / microbiology
  • Listeria monocytogenes / immunology*
  • Listeria monocytogenes / isolation & purification
  • Male
  • Mannans / analysis
  • Mannans / immunology*
  • Middle Aged

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Antigens, Fungal
  • Antineoplastic Agents
  • Mannans
  • galactomannan
  • Galactose