Herein, we report the facile synthesis of mesoporous NiCo(2)O(4) nanoflakes and their application in nonaqueous Li-O(2) batteries as cathode catalysts. The assembled Li-O(2) batteries presented lower overpotentials and enhanced cyclability, which should be attributed to the superior electrocatalytic activity and the mesoporous nanostructure of NiCo(2)O(4).