Electrosprayed nanoparticles for drug delivery and pharmaceutical applications

Biomatter. 2013 Jul-Sep;3(3):e24281. doi: 10.4161/biom.24281. Epub 2013 Mar 19.

Abstract

Nanotechnology based Pharma has emerged significantly and has influenced the Pharma industry up to a considerable extent. Nanoparticles technology holds a good share of the nanotech Pharma and is significant in comparison with the other domains. Electrospraying technology answers the potential needs of nanoparticle production such as scalability, reproducibility, effective encapsulation etc. Many drugs have been electrosprayed with and without polymer carriers. Drug release characteristics are improved with the incorporation of biodegradable polymer carriers which sustain the release of encapsulated drug. Electrospraying is acknowledged as an important technique for the preparation of nanoparticles with respect to pharmaceutical applications. Herein we attempted to consolidate the reports pertaining to electrospraying and their corresponding therapeutic application area.

Keywords: drug delivery; electrospray; nanomedicine; nanoparticle; sustained release.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Drug Compounding / methods
  • Drug Delivery Systems / methods*
  • Electrochemistry / methods*
  • Humans
  • Nanoparticles / administration & dosage*
  • Nanoparticles / chemistry
  • Nanotechnology / methods
  • Technology, Pharmaceutical / methods