Aorto-iliac aneurysm infected by Brucella: distinctive presentation patterns of a rare entity

Vascular. 2013 Oct;21(5):307-15. doi: 10.1177/1708538113478777. Epub 2013 May 7.

Abstract

There is currently a lack of information on presentation patterns and the appropriate investigation and treatment of aortic brucellosis. Herein a case affecting the iliac component of an aorto-iliac aneurysm, managed successfully with in situ graft repair, is reported. A review of the literature identified 25 cases, with the infrarenal abdominal aorta (65%) followed by the ascending thoracic aorta (23%) being mostly affected; only our case involved the iliacs. Aortic brucellosis affected mostly older men, caused pain more often than fever (in 73% and 57%, respectively), and involved frequently the spine or the aortic valve (n = 14, 56%). Preoperative diagnosis was made more often in the presence of fever (67% versus 18% in afebrile patients, P = 0.021). In situ aneurysm repair in the form of open (54%) or endovascular (8%) grafting was mostly performed. Mortality was 12% and graft infection was 13% at two years. In conclusion, aortic brucellosis has unique presentation patterns, usually affecting an abnormal or aneurysmal aorta and/or due to a contiguous spinal or aortic valve infection. Acute symptomatology with pain and/or fever occurs very often and should raise suspicion for aortic infection. Despite the seriousness of aortic involvement, mortality and reinfection rates are within acceptable levels.

Keywords: Brucella; aneurysm repair; aortic infection.

Publication types

  • Case Reports
  • Meta-Analysis
  • Review

MeSH terms

  • Adult
  • Aged
  • Aneurysm, Infected / diagnostic imaging
  • Aneurysm, Infected / microbiology
  • Aneurysm, Infected / surgery*
  • Anti-Bacterial Agents / therapeutic use
  • Aortic Aneurysm, Abdominal / diagnostic imaging
  • Aortic Aneurysm, Abdominal / microbiology
  • Aortic Aneurysm, Abdominal / surgery*
  • Aortography / methods
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Brucella / pathogenicity*
  • Brucellosis / diagnosis
  • Brucellosis / microbiology
  • Brucellosis / surgery*
  • Computed Tomography Angiography
  • Female
  • Humans
  • Iliac Aneurysm / diagnostic imaging
  • Iliac Aneurysm / microbiology
  • Iliac Aneurysm / surgery*
  • Male
  • Middle Aged
  • Postoperative Complications / etiology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents