Cytophagic histiocytic panniculitis in a 74-year-old man

Hiroyuki Hounoki; Hirofumi Taki; Reina Tsuda; Koichiro Shinoda; Kazuhiro Nomoto; Kazuyuki Tobe

doi:10.1093/ageing/aft034

Cytophagic histiocytic panniculitis in a 74-year-old man

Age Ageing. 2013 May;42(3):409-10. doi: 10.1093/ageing/aft034. Epub 2013 Mar 18.

Authors

Hiroyuki Hounoki¹, Hirofumi Taki, Reina Tsuda, Koichiro Shinoda, Kazuhiro Nomoto, Kazuyuki Tobe

Affiliation

¹ First Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama 930-0194, Japan.

PMID: 23507499
DOI: 10.1093/ageing/aft034

Abstract

Cytophagic histiocytic panniculitis is a chronic histiocytic disease of the subcutaneous adipose tissue characterised by lobular panniculitis with histiocytes containing blood cell fragments. It is also associated with marked systemic features such as fever, pancytopenia, hepatosplenomegaly, liver abnormalities and coagulopathy. We report a case of cytophagic histiocytic panniculitis in a 74-year-old man successfully treated using combination therapy with prednisolone and cyclosporine A.

Publication types

Case Reports

MeSH terms

Aged
Cyclosporine / therapeutic use
Cytophagocytosis*
Drug Therapy, Combination
Gallium Radioisotopes
Glucocorticoids / therapeutic use
Histiocytosis / classification*
Histiocytosis / diagnosis
Histiocytosis / drug therapy
Humans
Immunosuppressive Agents / therapeutic use
Male
Methylprednisolone / therapeutic use
Panniculitis / classification*
Panniculitis / diagnosis
Panniculitis / drug therapy
Prednisolone / therapeutic use
Treatment Outcome
Whole Body Imaging

Substances

Gallium Radioisotopes
Glucocorticoids
Immunosuppressive Agents
Cyclosporine
Prednisolone
Methylprednisolone