Rapid analysis of six phthalate esters in wine by ultrasound-vortex-assisted dispersive liquid-liquid micro-extraction coupled with gas chromatography-flame ionization detector or gas chromatography-ion trap mass spectrometry

Giuseppe Cinelli; Pasquale Avino; Ivan Notardonato; Angela Centola; Mario Vincenzo Russo

doi:10.1016/j.aca.2013.01.031

Rapid analysis of six phthalate esters in wine by ultrasound-vortex-assisted dispersive liquid-liquid micro-extraction coupled with gas chromatography-flame ionization detector or gas chromatography-ion trap mass spectrometry

Anal Chim Acta. 2013 Mar 26:769:72-8. doi: 10.1016/j.aca.2013.01.031. Epub 2013 Jan 24.

Authors

Giuseppe Cinelli¹, Pasquale Avino, Ivan Notardonato, Angela Centola, Mario Vincenzo Russo

Affiliation

¹ Dipartimento di Agricoltura, Ambiente e Alimenti, Università del Molise, via de Sanctis, Campobasso, Italy.

PMID: 23498123
DOI: 10.1016/j.aca.2013.01.031

Abstract

An Ultrasound-Vortex-Assisted Dispersive Liquid-Liquid Micro-Extraction (USVADLLME) procedure coupled with Gas Chromatography-Flame Ionization Detector (GC-FID) or Gas Chromatography-Ion Trap Mass Spectrometry (GC-IT/MS) is proposed for rapid analysis of six phthalate esters in hydroalcoholic beverages (alcohol by volume, alc vol(-1), ≤40%). Under optimal conditions, the enrichment factor of the six analytes ranges from 220- to 300-fold and the recovery from 85% to 100.5%. The limit of detection (LOD) and limit of quantification (LOQ) are ≥0.022 μg L(-1) and ≥0.075 μg L(-1), respectively. Intra-day and inter-day precisions expressed as relative standard deviation (RSD), are ≤8.2% and ≤7.0%, respectively. The whole proposed methodology has demonstrated to be simple, reproducible and sensible for the determination of trace phthalate esters in red and white wine samples.