Flow-through immobilized enzyme reactors based on monoliths: II. Kinetics study and application

J Sep Sci. 2013 Mar;36(6):1149-67. doi: 10.1002/jssc.201201090.

Abstract

In the last decade, the application of monolithic materials has rapidly expanded to the realization of flow-through bioconversion processes. Up to these days, different classes of enzymes such as hydrolases, lyases, and oxidoreductases have been immobilized on organic, inorganic, or hybrid monolithic materials to prepare the effective flow-through enzymes reactors for application in proteomics, biotechnology, pharmaceutics, organic synthesis, and biosensoring. Current review describes the results of kinetic study and specialties of flow-through immobilized enzyme reactors based on the existing monolithic materials.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bioreactors
  • Biotechnology / instrumentation*
  • Biotechnology / methods
  • Enzymes, Immobilized / chemistry*
  • Kinetics
  • Resins, Synthetic / chemistry*

Substances

  • Enzymes, Immobilized
  • Resins, Synthetic