Carbon-dots derived from nanodiamond: photoluminescence tunable nanoparticles for cell imaging

J Colloid Interface Sci. 2013 May 1:397:39-44. doi: 10.1016/j.jcis.2013.01.063. Epub 2013 Feb 8.

Abstract

Water dispersible carbon-dots (CDs) with tunable photoluminescence were synthesized via one-pot hydrothermal oxidation of nanodiamond and subsequently utilized for cell imaging applications. The CDs were characterized by the following techniques including transmission electron microscopy, atomic force microscopy, Fourier transform infrared spectroscopy, UV-Visible spectroscopy, and fluorescent spectroscopy. Results showed that the size of CDs is mainly distributed at 3-7 nm. Many functional groups were introduced on the surface of CDs during hydrothermal oxidation procedure. Cell morphology observation and cell viability measurement demonstrated the good biocompatibility of CDs, suggesting their potential bioimaging applications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Carbon / chemistry*
  • Carbon / pharmacology
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Humans
  • Mice
  • Microscopy, Fluorescence
  • NIH 3T3 Cells
  • Nanodiamonds / chemistry*
  • Spectrometry, Fluorescence
  • Spectroscopy, Fourier Transform Infrared

Substances

  • Nanodiamonds
  • Carbon