Leishmania amastigotes in neoplastic cells of 3 nonhistiocytic canine tumors

S Ferro; C Palmieri; L Cavicchioli; G De Zan; L Aresu; S L Benali

doi:10.1177/0300985813480192

Leishmania amastigotes in neoplastic cells of 3 nonhistiocytic canine tumors

Vet Pathol. 2013 Sep;50(5):749-52. doi: 10.1177/0300985813480192. Epub 2013 Mar 12.

Authors

S Ferro¹, C Palmieri, L Cavicchioli, G De Zan, L Aresu, S L Benali

Affiliation

¹ Faculty of Veterinary Medicine, Department of Comparative Biomedicine and Food Science, viale dell'università 16, Legnaro, Italy. silvia.ferro@unipd.it

PMID: 23482523
DOI: 10.1177/0300985813480192

Abstract

Concurrent leishmaniasis and neoplasia has been reported in dogs. This study describes the presence of the protozoa within the cytoplasm of neoplastic cells in 3 different types of tumors. Leishmania amastigotes were detected by light and transmission electron microscopy and immunohistochemistry in a fibrosarcoma, a T-cell lymphoma, and an adrenocortical adenoma.

Keywords: Leishmania; canine neoplasms; immunohistochemistry; ultrastructure.

Publication types

Case Reports

MeSH terms

Adrenocortical Adenoma / parasitology
Adrenocortical Adenoma / pathology
Adrenocortical Adenoma / veterinary*
Animals
Cytoplasm / parasitology
Dog Diseases / parasitology*
Dog Diseases / pathology*
Dogs
Enzyme-Linked Immunosorbent Assay / veterinary
Female
Fibrosarcoma / parasitology
Fibrosarcoma / pathology
Fibrosarcoma / veterinary*
Immunohistochemistry / veterinary
Leishmaniasis / pathology
Leishmaniasis / veterinary*
Lymphoma, T-Cell / parasitology
Lymphoma, T-Cell / pathology
Lymphoma, T-Cell / veterinary*
Male
Microscopy, Electron, Transmission / veterinary