Genetic characterization of IncI2 plasmids carrying blaCTX-M-55 spreading in both pets and food animals in China

Antimicrob Agents Chemother. 2013 Jun;57(6):2824-7. doi: 10.1128/AAC.02155-12. Epub 2013 Mar 11.

Abstract

pHN1122-1 carrying bla(CTX-M-55), from an Escherichia coli isolate from a dog, was completely sequenced. pHN1122-1 has an IncI2 replicon and typical IncI2-associated genetic modules, including mok/hok-finO-yafA/B, nikABC, and two transfer regions, tra and pil, as well as a shufflon. bla(CTX-M-55) is found within a 3.084-kb ISEcp1 transposition unit that includes a fragment of IncA/C plasmid backbone. pHN1122-1 and closely related plasmids were identified in other E. coli isolates from animals in China.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cats
  • China
  • Conjugation, Genetic
  • Dogs
  • Escherichia coli / genetics*
  • Escherichia coli Infections / microbiology
  • Escherichia coli Infections / veterinary*
  • Molecular Sequence Data
  • Pets / microbiology*
  • Plasmids / genetics*
  • Polymerase Chain Reaction
  • Poultry / microbiology*
  • Replicon / genetics*
  • Sequence Analysis, DNA
  • beta-Lactamases / genetics*

Substances

  • beta-Lactamases

Associated data

  • GENBANK/JN797501