Methyl 4-(4-chloro-phen-yl)-8-iodo-2-methyl-6-oxo-1,6-dihydro-4H-pyrimido[2,1-b]quinazoline-3-carboxyl-ate

Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o123-4. doi: 10.1107/S1600536812050787. Epub 2012 Dec 22.

Abstract

In the title compound, C20H15ClIN3O3, the dihedral angle between the quinazolinone ring system [r.m.s. deviation = 0.047 (2) Å] and the pendant benzene ring is 82.63 (11)°. The mol-ecular conformation is stabilized by intra-molecular C-H⋯O inter-actions. In the crystal, the mol-ecules are linked by N-H⋯O hydrogen bonds into chains along the a-axis direction. Another set of chains propagating along [101] is formed due to inter-molecular I⋯Cl short contacts of 3.427 (1) Å, thus giving layers parallel to (010). The layers are connected by C-H⋯π and π-π inter-actions, the shortest distance between the centroids of aromatic rings being 3.8143 (16) Å.