Preparation of cobalt-tetraphenylporphyrin/reduced graphene oxide nanocomposite and its application on hydrogen peroxide biosensor

Anal Chim Acta. 2013 Mar 20:768:69-75. doi: 10.1016/j.aca.2013.01.019. Epub 2013 Jan 21.

Abstract

A novel cobalt-tetraphenylporphyrin/reduced graphene oxide (CoTPP/RGO) nanocomposite was prepared by a π-π stacking interaction and characterized by ultraviolet-visible absorption spectroscopy (UV-vis), Fourier transform infrared spectroscopy (FTIR) and electrochemical impedance spectroscopy (EIS). The CoTPP/RGO nanocomposite exhibited high electrocatalytic activity both for oxidation and reduction of H2O2. The current response was linear to H2O2 concentration with the concentration range from 1.0×10(-7) to 2.4×10(-3)molL(-1) (R=0.998) at the reductive potential of -0.20V and from 1.0×10(-7) to 4.6×10(-4)molL(-1) (R=0.996) at the oxidative potential of +0.50V. The H2O2 biosensor showed good anti-interfering ability towards oxidative interferences at the oxidative potential of +0.50V and good anti-interfering ability towards reductive interferences at the reductive potential of -0.20V.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques*
  • Cobalt / chemistry*
  • Dielectric Spectroscopy
  • Electrochemical Techniques
  • Electrodes
  • Graphite / chemistry*
  • Hydrogen Peroxide / analysis*
  • Nanocomposites / chemistry*
  • Oxidation-Reduction
  • Oxides / chemistry
  • Porphyrins / chemistry*

Substances

  • Oxides
  • Porphyrins
  • tetraphenylporphyrin
  • Cobalt
  • Graphite
  • Hydrogen Peroxide