Streptococcus agalactiae infection in domestic rabbits, Oryctolagus cuniculus

Transbound Emerg Dis. 2014 Dec;61(6):e92-5. doi: 10.1111/tbed.12073. Epub 2013 Mar 7.

Abstract

Streptococcus agalactiae (Group B streptococcus, GBS) has emerged as an important pathogen that affects humans and animals, including aquatic species. In August 2011, a severe infectious disease affecting rabbits, which caused 42% mortality, occurred in Mianyang, Sichuan Province, China. The main clinical signs included acute respiratory distress syndrome, fever, paddling and convulsions. A Gram-positive, chain-forming coccus was isolated from the primary organs and tissues of diseased rabbits and then identified as S. agalactiae by morphology, biochemical and physiological characteristics, 16S rDNA and gyrB gene sequences analysis. All isolates of S. agalactiae showed a similar antibiotic susceptibility, which were sensitive to florfenicol, ampicillin,gentamicin and norfloxacin, as well as being resistant to penicillin, amoxicillin and tetracycline. To our knowledge, this is the first report on S. agalactiae natural infection in domestic rabbits.

Keywords: Streptococcus agalactiae; antimicrobial susceptibility; identification; rabbit.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • China / epidemiology
  • Disease Outbreaks / veterinary
  • Humans
  • RNA, Ribosomal, 16S / analysis
  • Rabbits
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / epidemiology
  • Streptococcal Infections / microbiology
  • Streptococcal Infections / veterinary*
  • Streptococcus agalactiae* / drug effects
  • Streptococcus agalactiae* / genetics

Substances

  • Anti-Bacterial Agents
  • RNA, Ribosomal, 16S