Mycobacterium abscessus complex lung infection in a toddler with a tracheostomy

Pediatr Pulmonol. 2014 Mar;49(3):296-8. doi: 10.1002/ppul.22789. Epub 2013 Mar 4.

Abstract

Mycobacterium abscessus complex and other non-tuberculous mycobacteria are infrequently encountered respiratory pathogens in patients with tracheostomies. We report a 4-year-old girl with a tracheostomy, placed during infancy for management of severe bronchopulmonary dysplasia and laryngeal stenosis, who developed a M. abscessus complex lung infection. There was clear evidence of parenchymal involvement and true infection beyond colonization. She demonstrated dramatic clinical, laboratory, and radiographic improvement after prolonged anti-mycobacterial therapy.

Keywords: child; non-tuberculous mycobacteria; tracheostomy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amikacin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Bronchopulmonary Dysplasia / complications
  • Child, Preschool
  • Clarithromycin / therapeutic use
  • Female
  • Humans
  • Laryngostenosis / complications
  • Laryngostenosis / surgery*
  • Minocycline / analogs & derivatives
  • Minocycline / therapeutic use
  • Mycobacterium Infections, Nontuberculous / complications
  • Mycobacterium Infections, Nontuberculous / diagnostic imaging*
  • Mycobacterium Infections, Nontuberculous / drug therapy
  • Tigecycline
  • Tomography, X-Ray Computed
  • Tracheostomy*
  • Tuberculosis, Pulmonary / complications
  • Tuberculosis, Pulmonary / diagnostic imaging*
  • Tuberculosis, Pulmonary / drug therapy

Substances

  • Anti-Bacterial Agents
  • Tigecycline
  • Amikacin
  • Minocycline
  • Clarithromycin