The effectiveness of early treatment in segmental vitiligo: retrospective study according to disease duration

Photodermatol Photoimmunol Photomed. 2013 Apr;29(2):103-5. doi: 10.1111/phpp.12029.

Abstract

Segmental vitiligo (SV) is usually characterized by a unilateral-dermatomal distribution, earlier onset and rapid progression followed by stabilization. The response to phototherapy in patients with SV is limited. We evaluated the treatment response in 39 cases of SV according to disease duration. Ten cases (50.0%) of Group 1 (duration ≤ 5 months) and five cases (26.3%) of Group 2 (duration > 5 months) showed more than 50% repigmentation. Contrary to previous reports, patients in our study responded well to medical treatments like oral steroids, topical calcineurin inhibitors and phototherapy when treated early after onset. The results suggest that early treatment is important.

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Middle Aged
  • Phototherapy*
  • Retrospective Studies
  • Steroids / therapeutic use
  • Tacrolimus / therapeutic use
  • Time Factors
  • Vitiligo / therapy*
  • Young Adult

Substances

  • Adrenal Cortex Hormones
  • Immunosuppressive Agents
  • Steroids
  • Tacrolimus