Oxime-based carbonates as useful reagents for both N-protection and peptide coupling

Molecules. 2012 Dec 5;17(12):14361-76. doi: 10.3390/molecules171214361.

Authors

Yahya El-Sayed Jad¹, Sherine N Khattab, Ayman El-Faham, Fernando Albericio

Affiliation

¹ Department of Chemistry, Faculty of Science, Alexandria University, P.O. Box 426, Ibrahimia, 21321 Alexandria, Egypt.

Abstract

We have demonstrated that oxime-based mixed carbonates are very effective reagents for both N-protection and peptide coupling.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carbonates / analysis
Carbonates / chemistry*
Indicators and Reagents / analysis
Indicators and Reagents / chemistry
Oximes / analysis
Oximes / chemistry*
Peptides / chemistry*

Substances

Carbonates
Indicators and Reagents
Oximes
Peptides