Quit stalling or you'll be silenced

Karen S Kim Guisbert; Erik J Sontheimer

doi:10.1016/j.cell.2013.02.025

Quit stalling or you'll be silenced

Cell. 2013 Feb 28;152(5):938-9. doi: 10.1016/j.cell.2013.02.025.

Authors

Karen S Kim Guisbert¹, Erik J Sontheimer

Affiliation

¹ Department of Molecular Biosciences, Northwestern University, 2205 Tech Drive, Evanston, IL 60208-3500, USA.

PMID: 23452843
DOI: 10.1016/j.cell.2013.02.025

Abstract

The use of small RNAs to program gene regulation and genome defense necessitates ever-changing choices about the sequences used for small-RNA biogenesis. Dumesic et al. now reveal stalled spliceosomes as a trigger for small-RNA biogenesis in the pathogenic fungus Cryptococcus neoformans.

Publication types

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