Asymmetric hydroamination: a survey of the most recent developments

Chemistry. 2013 Apr 15;19(16):4972-85. doi: 10.1002/chem.201203956. Epub 2013 Mar 1.

Abstract

Asymmetric hydroamination allows the direct and selective formation of a new C-N bond as a simple procedure towards valuable scalemic synthons. Huge efforts have recently been made to overcome the challenges associated with this transformation. This non-comprehensive Concept article aims at pointing out the most recent and original progresses, offering nearby developments, and addressing the next challenges.

MeSH terms

  • Amination
  • Amines / chemistry*
  • Catalysis
  • Cyclization
  • Metals / chemistry*

Substances

  • Amines
  • Metals