Antibiotic prescribing in DR Congo: a knowledge, attitude and practice survey among medical doctors and students

PLoS One. 2013;8(2):e55495. doi: 10.1371/journal.pone.0055495. Epub 2013 Feb 18.

Abstract

Objectives: Antibiotic resistance (ABR) particularly hits resource poor countries, and is fuelled by irrational antibiotic (AB) prescribing. We surveyed knowledge, attitudes and practices of AB prescribing among medical students and doctors in Kisangani, DR Congo.

Methods: Self-administered questionnaires.

Results: A total of 184 questionnaires were completed (response rate 94.4%). Knowledge about AB was low (mean score 4.9/8 points), as was the estimation of local resistance rates of S. Typhi and Klebsiella spp.(correct by 42.5% and 6.9% of respondents respectively). ABR was recognized as a problem though less in their own practice (67.4%) than nation- or worldwide (92.9% and 85.5%, p<.0001). Confidence in AB prescribing was high (88.6%) and students consulted more frequently colleagues than medical doctors when prescribing (25.4% versus 11.6%, p= 0.19). Sources of AB prescribing included pharmaceutical companies (73.9%), antibiotic guidelines (66.3%), university courses (63.6%), internet-sites (45.7%) and WHO guidelines (26.6%). Only 30.4% and 16.3% respondents perceived AB procured through the central procurement and local pharmacies as of good quality. Local AB guidelines and courses about AB prescribing are welcomed (73.4% and 98.8% respectively).

Conclusions: This data shows the need for interventions that support rational AB prescribing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents* / therapeutic use
  • Congo
  • Cross-Sectional Studies
  • Drug Prescriptions*
  • Drug Resistance, Microbial
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Physicians*
  • Practice Patterns, Physicians'
  • Risk Factors
  • Students, Medical*
  • Surveys and Questionnaires

Substances

  • Anti-Bacterial Agents

Grants and funding

This study was sponsored by the Flemish Interuniversity Council Project ZRDC2009EIN6. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.