On the chaos in gene networks

J Bioinform Comput Biol. 2013 Feb;11(1):1340009. doi: 10.1142/S021972001340009X. Epub 2013 Feb 6.

Abstract

The methods for constructing "chaotic" nonlinear systems of differential equations modeling gene networks of arbitrary structure and dimensionality with various types of symmetry are considered. It has been shown that an increase in modality of the functions describing the control of gene expression efficiency allows for a decrease in the dimensionality of these systems with retention of their chaotic dynamics. Three-dimensional "chaotic" cyclic systems are considered. Symmetrical and asymmetrical attractors with "narrow" chaos having a Moebius-like structure have been detected in such systems. As has been demonstrated, a complete symmetry of the systems with respect to permutation of variables does not prevent the emergence of their chaotic dynamics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Computer Simulation
  • Gene Expression Regulation / genetics*
  • Humans
  • Models, Genetic*
  • Nonlinear Dynamics*
  • Proteome / genetics*
  • Signal Transduction / genetics*

Substances

  • Proteome