The aim of the present study was to evaluate the shear bond strength test of two glass-ionomer cements (G C cement and Ketac Bond) after different chemical pretreatments of dentine surface. The following dentine pretreatments were used: sodium hypochlorite, polyacrylic acid, tannic acid, H3PO4, FeCl3, Fe ossalate, Tubulicid, H2O2 and aqueous solution as control. Flat dentine surface of human extracted teeth was treated with the chemical agents, washed and dried. Cylindrical specimens of glass-ionomer cement were applied on dentine surface. After 24 hours in humidifier the specimens were tested in a universal testing machine. A significant higher bond was obtained only from polyacrylic acid and sodium hypochlorite treatments. The present results suggest that dentine pretreatment represent an essential step in composite resin/glass-ionomer cement restorations.