(1SR,3RS,3aSR,6aRS)-Methyl 5-methyl-4,6-dioxo-3-[2-(trifluoro-meth-yl)phen-yl]octa-hydro-pyrrolo-[3,4-c]pyrrole-1-carboxyl-ate

Acta Crystallogr Sect E Struct Rep Online. 2013 Feb 1;69(Pt 2):o161-2. doi: 10.1107/S1600536812051471. Epub 2013 Jan 4.

Abstract

In the title compound, C(16)H(15)F(3)N(2)O(4), the relative stereochemistry of the four stereogenic C atoms has been determined. The carb-oxy-methyl and 2-(trifluoro-meth-yl)-phenyl substituents of the pyrrolidine cycle have a cis mutual arrangement. The five-membered saturated aza-cycle adopts an envelope conformation with the N atom occupying the flap position. In the crystal, adjacent mol-ecules are combined in centrosymmetric dimers by two weak N-H⋯O hydrogen bonds.