Abstract
Carboxylated SiO2-coated α-Fe nanoparticles have been successfully prepared via CaH2-mediated reduction of SiO2-coated Fe3O4 nanoparticles followed by surface carboxylation. These α-Fe-based nanoparticles, which are characterized by ease of coating with additional functional groups, a large magnetization of 154 emu per g-Fe, enhanced corrosion resistivity, excellent aqueous dispersibility, and low cytotoxicity, have potential to be a versatile platform in biomedical applications.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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CHO Cells
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Carboxylic Acids / chemistry*
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Cell Line, Tumor
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Cell Survival / drug effects
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Cricetinae
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Cricetulus
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Ferrosoferric Oxide / chemistry*
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Humans
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Magnetic Resonance Imaging
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Magnetite Nanoparticles / chemistry*
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Magnetite Nanoparticles / toxicity
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Neoplasms / diagnostic imaging
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Radiography
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Silicon Dioxide / chemistry*
Substances
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Carboxylic Acids
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Magnetite Nanoparticles
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Silicon Dioxide
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Ferrosoferric Oxide