Peripheral blood stem cell transplantation in a significant body weight difference between a smaller donor and a larger recipient: a case report

Abstract

Allogeneic peripheral blood stem cell transplantation (PBSCT) is becoming a common transplantation procedure in children. However, few benefits have been reported, in particular in regard to the choice of small children as donors for larger recipients. We report a case of relapsed acute myeloid leukemia (body weight 52 kg and blood type O) who underwent allogeneic PBSCT from his smaller human leukocyte antigen-matched brother (body weight 29.9 kg and blood type A).

Keywords: Benefits of younger donors; Peripheral blood stem cell collection; Peripheral blood stem cell transplantation; Safety of donors; Significant body weight difference.