Microbiologic isolates and risk factors associated with antimicrobial resistance in patients admitted to the intensive care unit in a tertiary care hospital

Am J Infect Control. 2013 Sep;41(9):846-8. doi: 10.1016/j.ajic.2012.11.010. Epub 2013 Feb 16.

Abstract

This study reviewed the clinical and microbiologic data for patients admitted to the intensive care unit with hospital-acquired infections. In the multivariate analysis, AIDS and previous antibiotic use were associated with the emergence of multiresistant bacteria. Hematologic diseases, length of stay, number of days on central venous catheter, antimicrobial use, and presence of multiresistant bacteria were associated with death. The previous use of antibiotics and the length of the hospital stay contribute to the development of infections caused by multiresistant gram-negative bacteria.

Keywords: Bacterial resistance; Nosocomial infection; Patient outcome.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacteria / drug effects*
  • Bacteria / isolation & purification
  • Bacterial Infections / epidemiology*
  • Bacterial Infections / microbiology*
  • Bacterial Infections / mortality
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology*
  • Cross Infection / mortality
  • Drug Resistance, Bacterial*
  • Drug Utilization
  • Female
  • Humans
  • Intensive Care Units
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Tertiary Care Centers

Substances

  • Anti-Bacterial Agents