Bronchopulmonary dysplasia: a review

Arch Gynecol Obstet. 2013 Aug;288(2):325-33. doi: 10.1007/s00404-013-2753-8. Epub 2013 Feb 19.

Abstract

Introduction: The prevalence of bronchopulmonary dysplasia (BPD), one of the most frequently occurring complications following preterm birth, is increasing due to increased survival of preterm infants.

Methods: Systematic literature review.

Conclusion: The etiology is multifactorial, with prematurity being a prerequisite for the development of BPD. Over time, there have been many different and new treatment modalities, some of them have reduced the severity of the disease, but none of them have been able to impact upon the increasing incidence of BPD.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Birth Weight*
  • Bronchopulmonary Dysplasia / etiology*
  • Bronchopulmonary Dysplasia / genetics
  • Bronchopulmonary Dysplasia / prevention & control
  • Bronchopulmonary Dysplasia / therapy*
  • Caffeine / therapeutic use
  • Female
  • Gestational Age*
  • Humans
  • Hyperoxia / complications
  • Infant, Newborn
  • Oxygen Inhalation Therapy
  • Phosphodiesterase Inhibitors / therapeutic use
  • Pregnancy
  • Pulmonary Surfactants / therapeutic use
  • Respiration, Artificial / adverse effects
  • Sex Factors
  • Vitamin A / therapeutic use
  • Vitamins / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Phosphodiesterase Inhibitors
  • Pulmonary Surfactants
  • Vitamins
  • Vitamin A
  • Caffeine