[Mild asthma in children: new data and a revival of interest]

Rev Mal Respir. 2013 Feb;30(2):115-24. doi: 10.1016/j.rmr.2012.10.002. Epub 2012 Nov 13.
[Article in French]

Abstract

According to the Global Initiative for Asthma (GINA) classification, mild asthma includes intermittent and mild persistent asthma. It represents more than 75% of asthmatic children. The symptoms and functional impact are well described. Mild asthma can lead to severe exacerbations. Progression to more severe disease may occur. Consequently, it is important to diagnose mild asthma, to initiate the appropriate treatment early, and to identify the risk factors for aggravation. Nevertheless, mild asthma is under-diagnosed and under-treated. Bronchial inflammation and remodeling are observed in mild asthma. A daily low-dose of inhaled corticosteroids is the reference treatment for mild persistent asthma. Intermittent inhaled corticosteroids cannot be recommended in children with mild persistent asthma.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / adverse effects
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Age of Onset
  • Airway Remodeling
  • Anti-Asthmatic Agents / adverse effects
  • Anti-Asthmatic Agents / therapeutic use
  • Asthma / diagnosis
  • Asthma / drug therapy
  • Asthma / epidemiology*
  • Asthma / physiopathology
  • Bronchitis / complications
  • Bronchitis / physiopathology
  • Child
  • Child, Preschool
  • Cohort Studies
  • Comorbidity
  • Contraindications
  • Disease Progression
  • Environmental Exposure
  • Female
  • Humans
  • Infant
  • Leukotriene Antagonists / therapeutic use
  • Male
  • Middle Aged
  • Obesity / epidemiology
  • Phenotype
  • Risk Factors
  • Sex Distribution
  • Symptom Assessment

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents
  • Leukotriene Antagonists