Advancing the modeling in particle therapy: from track structure to treatment planning

Appl Radiat Isot. 2014 Jan:83 Pt B:171-6. doi: 10.1016/j.apradiso.2013.01.019. Epub 2013 Jan 18.

Abstract

We present a series of implementations on Monte Carlo track structure level which might have an impact on treatment planning for particle therapy. We evaluated the effect of multiple ion scattering and radical diffusion on the nanoscopic radial dose. Our cross section database for electron interactions was extended to be able to predict the sensitizing effect of gold nanoparticles in particle therapy. We also implemented LiF as a possible target for efficiency calculations of thermoluminescent detectors (TLDs).

Keywords: Elastic scattering of ions; Electron excitation; Gold nanoparticles; Low-energy electrons; Track structure; Treatment planning.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Luminescence
  • Models, Theoretical*
  • Monte Carlo Method
  • Neoplasms / radiotherapy
  • Radiotherapy Dosage
  • Radiotherapy*