Antifungal activity of tetrahydroquinolines against some phytopathogenic fungi

Margarita Gutiérrez; Unai Carmona; Gabriel Vallejos; Luis Astudillo

doi:10.1515/znc-2012-11-1204

Antifungal activity of tetrahydroquinolines against some phytopathogenic fungi

Z Naturforsch C J Biosci. 2012 Nov-Dec;67(11-12):551-6. doi: 10.1515/znc-2012-11-1204.

Authors

Margarita Gutiérrez¹, Unai Carmona, Gabriel Vallejos, Luis Astudillo

Affiliation

¹ Laboratory of Organic Synthesis, Institute of Chemistry of Natural Resources, University of Talca, Casilla 747, Talca, Chile. mgutierrez@utalca.cl

PMID: 23413748
DOI: 10.1515/znc-2012-11-1204

Abstract

Seven synthetic tetrahydroquinolines with different substitution patterns were obtained by an imino Diels-Alder condensation reaction and were evaluated against phytopathogenic fungi. Compounds with a methoxy group showed interesting activity against Cladosporium cladosporoides with a MIC value of 13.75 microg/mL

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antifungal Agents / pharmacology*
Cladosporium / drug effects*
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Quinolines / pharmacology*
Spectrometry, Mass, Electrospray Ionization

Substances

Antifungal Agents
Quinolines
1,2,3,4-tetrahydroquinoline