Abstract
A total of 123 Shigella isolates were collected from SiXian area in Anhui, China. Screening was carried out by polymerase chain reaction (PCR) amplification of plasmid-mediated quinolone resistance (PMQR) determinants. Different β-blactamases genes, plasmid-borne bla(AmpC), 16S rRNA methylase genes, integrons, and mutations in quinolone resistance-determining regions were analysed by PCR for the PMQR-positive isolates.
Copyright © 2013 Elsevier Inc. All rights reserved.
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / genetics
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China / epidemiology
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Ciprofloxacin / pharmacology*
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DNA Gyrase / genetics
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DNA Topoisomerase IV / genetics
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Drug Resistance, Multiple, Bacterial*
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Dysentery, Bacillary / epidemiology
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Dysentery, Bacillary / microbiology
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Genes, Bacterial
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Genes, rRNA
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Humans
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Integrons
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Mutation
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Plasmids / genetics*
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Polymerase Chain Reaction / methods
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RNA, Ribosomal, 16S / genetics
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Shigella / drug effects*
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Shigella / genetics
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Shigella / isolation & purification
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beta-Lactamases / genetics
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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RNA, Ribosomal, 16S
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Ciprofloxacin
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AmpC beta-lactamases
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beta-Lactamases
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DNA Topoisomerase IV
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DNA Gyrase