Association of posttraumatic stress disorder and depression with all-cause and cardiovascular disease mortality and hospitalization among Hurricane Katrina survivors with end-stage renal disease

Am J Public Health. 2013 Apr;103(4):e130-7. doi: 10.2105/AJPH.2012.301146. Epub 2013 Feb 14.

Abstract

Objectives: We determined the association of psychiatric symptoms in the year after Hurricane Katrina with subsequent hospitalization and mortality in end-stage renal disease (ESRD) patients.

Methods: A prospective cohort of ESRD patients (n = 391) treated at 9 hemodialysis centers in the New Orleans, Louisiana, area in the weeks before Hurricane Katrina were assessed for posttraumatic stress disorder (PTSD) and depression symptoms via telephone interview 9 to 15 months later. Two combined outcomes through August 2009 (maximum 3.5-year follow-up) were analyzed: (1) all-cause and (2) cardiovascular-related hospitalization and mortality.

Results: Twenty-four percent of participants screened positive for PTSD and 46% for depression; 158 participants died (79 cardiovascular deaths), and 280 participants were hospitalized (167 for cardiovascular-related causes). Positive depression screening was associated with 33% higher risk of all-cause (hazard ratio [HR] = 1.33; 95% confidence interval [CI] = 1.06, 1.66) and cardiovascular-related hospitalization and mortality (HR = 1.33; 95% CI = 1.01, 1.76). PTSD was not significantly associated with either outcome.

Conclusions: Depression in the year after Hurricane Katrina was associated with increased risk of hospitalization and mortality in ESRD patients, underscoring the long-term consequences of natural disasters for vulnerable populations.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Cardiovascular Diseases / mortality*
  • Cardiovascular Diseases / psychology*
  • Cause of Death*
  • Depression / epidemiology*
  • Depression / psychology*
  • Female
  • Hospitalization / statistics & numerical data*
  • Humans
  • Interviews as Topic
  • Kidney Failure, Chronic / mortality*
  • Kidney Failure, Chronic / psychology*
  • Louisiana / epidemiology
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Prospective Studies
  • Psychiatric Status Rating Scales
  • Stress Disorders, Post-Traumatic / epidemiology*
  • Stress Disorders, Post-Traumatic / psychology*