Fractionation of phenolic compounds extracted from propolis and their activity in the yeast Saccharomyces cerevisiae

Tanja Petelinc; Tomaž Polak; Lea Demšar; Polona Jamnik

doi:10.1371/journal.pone.0056104

Fractionation of phenolic compounds extracted from propolis and their activity in the yeast Saccharomyces cerevisiae

PLoS One. 2013;8(2):e56104. doi: 10.1371/journal.pone.0056104. Epub 2013 Feb 7.

Authors

Tanja Petelinc¹, Tomaž Polak, Lea Demšar, Polona Jamnik

Affiliation

¹ Department of Food Science and Technology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.

Abstract

We have here investigated the activities of Slovenian propolis extracts in the yeast Saccharomyces cerevisiae, and identified the phenolic compounds that appear to contribute to these activities. We correlated changes in intracellular oxidation and cellular metabolic energy in these yeasts with the individual fractions of the propolis extracts obtained following solid-phase extraction. The most effective fraction was further investigated according to its phenolic compounds.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Energy Metabolism
Intracellular Space / metabolism
Oxidation-Reduction
Phenols / isolation & purification*
Phenols / metabolism*
Propolis / chemistry*
Saccharomyces cerevisiae / chemistry*
Saccharomyces cerevisiae / cytology
Saccharomyces cerevisiae / metabolism*

Substances

Phenols
Propolis

Grants and funding

This work was partly supported by European Social Fund within the National Programme -Innovative scheme for funding the doctoral program (278–246). No additional external funding received for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.