Should aortic valve reimplantation be offered to patients with a large aorto-ventricular junction?

Eur J Cardiothorac Surg. 2013 May;43(5):e130-5. doi: 10.1093/ejcts/ezt052. Epub 2013 Feb 13.

Abstract

Objectives: Large aortic root aneurysms might increase leaflet stress and compromise aortic valve durability after the reimplantation technique. We analysed the impact of the preoperative aorto-ventricular junction (AVJ) diameter on the durability of the valve.

Methods: Between March 2004 and January 2012, 150 patients underwent the David operation on the aortic root. We identified 47 patients with a preoperative AVJ >28 mm (Group A) and 103 patients with a diameter ≤ 28 mm (Group B). The mean follow-up was 44 ± 27 months. Both groups were compared regarding mortality, freedom from moderate or severe aortic valve regurgitation and freedom from reoperation.

Results: Early mortality was 1.3%. Actuarial survival at 1, 3 and 5 years was 97 ± 2, 94 ± 3 and 94 ± 3% for Group A, and 99 ± 1, 97 ± 1 and 94 ± 3% for Group B, respectively (P = 0.3). Two patients in Group B were reoperated for severe aortic regurgitation (AR). Actuarial freedom from reoperation at 1, 3 and 5 years was 100% for Group A, and 98 ± 1, 98 ± 1 and 96 ± 2% for Group B, respectively (P = 0.3). During the follow-up, 6 patients (3 in each group) developed AR ≥ Grade II. Therefore, actuarial freedom from AR grade II or greater at 1.3 and 5 years was 97 ± 2, 94 ± 4 and 87 ± 7% for Group A, and 99 ± 1, 97 ± 1 and 95 ± 2% for Group B (P = 0.3).

Conclusions: The reimplantation technique shows excellent results. Medium-term stability of the aortic valve repair was not influenced by the preoperative aorto-ventricular junction diameter.

MeSH terms

  • Adult
  • Aged
  • Aorta / anatomy & histology
  • Aortic Aneurysm / surgery
  • Aortic Valve / anatomy & histology
  • Aortic Valve / surgery*
  • Aortic Valve Insufficiency / etiology
  • Cardiac Surgical Procedures / methods*
  • Contraindications
  • Female
  • Heart Ventricles / anatomy & histology
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Perioperative Period
  • Reoperation
  • Replantation / methods*