Use of glycopyrrolate and atropine in acute organophosphorus poisoning

Hum Exp Toxicol. 1990 Mar;9(2):99-100. doi: 10.1177/096032719000900207.

Abstract

Two cases of organophosphorus poisoning are reported. Both were treated with a combination of atropine and glycopyrrolate as well as benzodiazepine and pralidoxime. The advantages of glycopyrrolate over atropine are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Atropine / therapeutic use*
  • Diazepam / therapeutic use
  • Drug Therapy, Combination
  • Glycopyrrolate / therapeutic use*
  • Humans
  • Insecticides / poisoning
  • Male
  • Midazolam / therapeutic use
  • Nervous System Diseases / chemically induced
  • Nervous System Diseases / physiopathology
  • Organophosphate Poisoning*
  • Organothiophosphorus Compounds / poisoning
  • Phosmet / poisoning
  • Pralidoxime Compounds / therapeutic use
  • Pyrrolidines / therapeutic use*

Substances

  • Insecticides
  • Organothiophosphorus Compounds
  • Pralidoxime Compounds
  • Pyrrolidines
  • isofenphos
  • Atropine
  • Diazepam
  • Midazolam
  • Glycopyrrolate
  • Phosmet