Abstract
The first electrochemical immunosensor (EI) for the detection of antibodies against deamidated gliadin peptides (DGP) is described here. A disposable nanohybrid screen-printed carbon electrode modified with DGP was employed as the transducer's sensing surface. Real serum samples were successfully assayed and the results were corroborated with an ELISA kit. The presented EI is a promising analytical tool for celiac disease diagnosis.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Antibodies / blood
-
Biosensing Techniques / methods*
-
Celiac Disease / diagnosis*
-
Celiac Disease / immunology
-
Gliadin / immunology*
-
Gliadin / metabolism
-
Humans
-
Immunoassay / methods
-
Immunoglobulin G / analysis
-
Nanotubes, Carbon
-
Peptide Fragments / immunology
-
Transglutaminases / metabolism
Substances
-
Antibodies
-
Immunoglobulin G
-
Nanotubes, Carbon
-
Peptide Fragments
-
Gliadin
-
Transglutaminases