Psychosocial implications and the duality of life outcomes for patients with prostate carcinoma after bilateral orchiectomy

Neuro Endocrinol Lett. 2012;33(8):761-4.

Abstract

Objectives: The study presented focuses on patients' psychosocial status after a prostate cancer diagnosis that underwent a bilateral orchiectomy.

Methods: We evaluated the psychosocial implications of 89 patients with prostate cancer after performing castration and a bilateral orchiectomy.

Results: Patients suffered significantly more from sleep disorders during hospitalisation when compared to their time prior to an orchiectomy (p<0.0005). There were some increases in the severity of sleep disorder after discharge (level of evidence p<0.05). However, no additional medications for sleep disorders were required. Additionally, there was a significant reduction in the abuse of medication (p<0.001). Ten per cent of the patients were in the care of a psychologist or a psychiatrist before their diagnosis, and 21% asked for the help of a psychologist or a psychiatrist after having a bilateral orchiectomy. The occurrence of mood disorders is also very different than the occurrence of sleep disorders. Mood disorders occurred much less often after orchiectomy and discharge (p>0.085) compared with the period before surgery. Forty per cent of the patients had mood disorders before their operation, while only 37% still had these after discharge. There was a significant decrease in abuse of medication for anxiety. Twenty-four per cent of the patients took medication during hospitalisation, and only 10% continued after orchiectomy.

Conclusions: The results of the study show that patients who were notified about their cancer diagnosis, particularly their health status, exhibited moderate stress and psychological impact.

MeSH terms

  • Affect
  • Aged
  • Aged, 80 and over
  • Anxiety Disorders / psychology
  • Humans
  • Male
  • Middle Aged
  • Orchiectomy / methods
  • Orchiectomy / psychology*
  • Palliative Care / psychology
  • Patient Satisfaction
  • Prostatic Neoplasms / psychology*
  • Prostatic Neoplasms / surgery*
  • Psychology
  • Quality of Life / psychology*
  • Stress, Psychological / psychology*
  • Suicide / psychology